An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE

Preprint posted on bioRxiv 10.1101/2024.12.30.630690

#Pin-Yi Song, #Chia-En Tsai, Yung-Chih Chen, Yu-Wen Huang, Po-Pang Chen, Tzu-Haw Wang, Chao-Yuan Hu, Po-Yin Chen, Chuan Ku, Kuo-Chiang Hsia, See-Yeun Ting (2025) (#co-first authors)

Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism

The EMBO Journal, 44: 2473 - 2500

#Chia-En Tsai, #Feng-Qi Wang, Chih-Wen Yang, Ling-Li Yang, Thao VP. Nguyen, Yung-Chih Chen, Po-Yin Chen, Ing-Shouh Hwang, See-Yeun Ting (2025) (#co-first authors) [Research Finding]

A Whole-Cell Platform for Discovering Synthetic Cell Adhesion Molecules in Bacteria

Nature Communications 15: 6568

Po-Yin Chen, Yung-Chih Chen, Po-Pang Chen, Kuan-Ting Lin, Karen Sargsyan, Chao-Ping Hsu, Wei-Le Wang, Kuo-Chiang Hsia, See-Yeun Ting (2024) [Research Finding]

Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism

eLife 11:e74658

See-Yeun Ting, Kaitlyn D. LaCourse, Hannah E. Ledvina, Rutan Zhang, Matthew C. Radey, Hemantha D. Kulasekara, Rahul Somavanshi, Savannah K. Bertolli, Larry A. Gallagher, Jennifer Kim, Kelsi M. Penewit, Stephen J. Salipante, Libin Xu, S. Brook Peterson, Joseph D. Mougous. (2022)

Targeted depletion of bacteria from mixed populations by programmable adhesion with antagonistic competitor cells.

Cell Host Microbe 28, 313-321.

#See-Yeun Ting, #Esteban Martínez-García, Shuo Huang, Savannah K Bertolli, Katherine A Kelly, Kevin J Cutler, Elizabeth D Su, Hui Zhi, Qing Tang, Matthew C Radey, Manuela Raffatellu, S Brook Peterson, Víctor de Lorenzo, Joseph D Mougous. (2020) (# authors contributed equally)

Bifunctional immunity proteins protect bacteria against FtsZ-targeting ADP-ribosylating toxins.

Cell 175, 1380-1392.e14.

Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23

See-Yeun Ting, Nicholas L Yan, Brenda A Schilke, Elizabeth A Craig. (2017)

Architecture of the TIM23 inner mitochondrial translocon and interactions with the matrix import motor.

J Biol Chem 10;289(41):28689-96.